Session Details

PM05: Survival Analysis in Decision Modeling
(Event: SMDM 40th Annual Meeting: Montreal, QC, Canada)

Oct 14, 2018 2:00PM - Oct 14, 2018 5:30PM
Session Type: Short Course- PM 1/2 Day

Description
 
Background
Economic evaluations often rely on input from time-to-event or survival data. The unique characteristics of such data (i.e. right skewness, non-negative values, competing risks, censoring) require the use of more advanced statistical modeling techniques. Consequently, incorporating input from such statistical models into a model-based economic evaluation can become challenging. In addition, the adoption of a lifetime horizon in economic evaluations requires extrapolation beyond the observed survival times, implying additional assumptions which complicate further the integration of survival models in economic evaluation. Finally, criticism has been raised recently on some common approaches used when integrating survival data in economic evaluations.
Course Type
Half Day
Course Level
Beginner
Format Requirements
The course will cover both basic and advanced methods in survival analysis methods for economic evaluation. Therefore, although there will be a gradual build-up of statistical concepts, some basic background in survival analysis is necessary. In addition, good understanding of decision modeling and basic knowledge of R is required. Participants will need to bring their own laptops for practical exercises. R and RStudio will need to be pre-installed. Installation instructions will follow prior to the course.
Overview
The course will offer an introduction to survival analysis methods for model- based economic evaluations. Practical examples of different economic evaluation scenarios that rely on survival analysis data will be presented. The advantages and disadvantages of each method will be discussed. All analyses will be conducted using the R statistical software.
Description & Objectives
This course will teach participants how to appropriately integrate survival analysis data in decision models using R. We will provide an overview of the available methods (e.g. partitioned survival analysis, multistate models, Markov/semi-Markov models) and the advantages and disadvantages of each. The implementation of these methods in R will be outlined. Course participants will be asked to complete simple survival analysis exercises in the context of decision modeling to familiarize with the main concepts. Finally, we will present more advanced examples using different types of data (patient-level, life tables, digitized data from published curves)

By the end of the course the participants will be able to:

 

  • Understand the advantages and limitations of the different survival analysis methods when used in an economic evaluation context.
  • Fit different parametric forms to survival data using R
  • Fit competing risks model and multistate models in R
  • Integrate the results of different survival analysis models in a decision modeling framework.

All R code used in the short course will be provided to participants for future use.

Course Director
Course Faculty

  

Session Fees
Fee TypeMember FeeNon-Member Fee
This session is free
Early: $200.00 $325.00
Regular: $245.00 $370.00
Late: $245.00 $370.00
This session is free
Early: $170.00 $170.00
Regular: $215.00 $215.00
Late: $215.00 $215.00

 

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